Searchable abstracts of presentations at key conferences in endocrinology

ea0022p625 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Efficacy and safety of co-administration of lanreotide Autogel 120 mg monthly with pegvisomant weekly in patients with acromegaly partially controlled by somatostatin analogues

van der Lely Aart-Jan , Bernabeu Ignacio , Cap Jan , Caron Philippe , Colao Annamaria , Lesage Catherine , Marek Josef , Neggers Sebastian , Birman Pascal

Recent studies have shown that the co-administration of lanreotide (lan) with pegvisomant (peg) was able to normalise IGF1 secretion in patients with acromegaly who were partial responders to somatostatin analogues (SSAs).Fifty seven subjects with acromegaly (mean age 51.6±12.7 years) not previously controlled by SSAs (either treated by SSAs for at least 6 months with IGF1 > ULN, or on peg for at least 3 months) with IGF1 > 1.2 ULN (n...